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SPI-1 is a missing host-range factor required for replication of the attenuated modified vaccinia Ankara (MVA) vaccine vector in human cells

Modified vaccinia virus Ankara (MVA) is the leading poxvirus vector for development of vaccines against diverse infectious diseases. This distinction is based on high expression of proteins and good immunogenicity despite an inability to assemble infectious progeny in human cells, which together pro...

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書目詳細資料
發表在:PLoS Pathog
Main Authors: Liu, Ruikang, Mendez-Rios, Jorge D., Peng, Chen, Xiao, Wei, Weisberg, Andrea S., Wyatt, Linda S., Moss, Bernard
格式: Artigo
語言:Inglês
出版: Public Library of Science 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542542/
https://ncbi.nlm.nih.gov/pubmed/31145755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007710
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