SPI-1 is a missing host-range factor required for replication of the attenuated modified vaccinia Ankara (MVA) vaccine vector in human cells

Modified vaccinia virus Ankara (MVA) is the leading poxvirus vector for development of vaccines against diverse infectious diseases. This distinction is based on high expression of proteins and good immunogenicity despite an inability to assemble infectious progeny in human cells, which together pro...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Pathog
Hauptverfasser: Liu, Ruikang, Mendez-Rios, Jorge D., Peng, Chen, Xiao, Wei, Weisberg, Andrea S., Wyatt, Linda S., Moss, Bernard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542542/
https://ncbi.nlm.nih.gov/pubmed/31145755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007710
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