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Repair of a previously uncharacterized second host-range gene contributes to full replication of modified vaccinia virus Ankara (MVA) in human cells

Modified vaccinia virus Ankara (MVA), a widely used vaccine vector for expression of genes of unrelated pathogens, is safe, immunogenic, and can incorporate large amounts of added DNA. MVA was derived by extensively passaging the chorioallantois vaccinia virus Ankara (CVA) vaccine strain in chicken...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Peng, Chen, Moss, Bernard
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035496/
https://ncbi.nlm.nih.gov/pubmed/32019881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921098117
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