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Repair of a previously uncharacterized second host-range gene contributes to full replication of modified vaccinia virus Ankara (MVA) in human cells

Modified vaccinia virus Ankara (MVA), a widely used vaccine vector for expression of genes of unrelated pathogens, is safe, immunogenic, and can incorporate large amounts of added DNA. MVA was derived by extensively passaging the chorioallantois vaccinia virus Ankara (CVA) vaccine strain in chicken...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Peng, Chen, Moss, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035496/
https://ncbi.nlm.nih.gov/pubmed/32019881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921098117
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