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Repair of a previously uncharacterized second host-range gene contributes to full replication of modified vaccinia virus Ankara (MVA) in human cells

Modified vaccinia virus Ankara (MVA), a widely used vaccine vector for expression of genes of unrelated pathogens, is safe, immunogenic, and can incorporate large amounts of added DNA. MVA was derived by extensively passaging the chorioallantois vaccinia virus Ankara (CVA) vaccine strain in chicken...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Peng, Chen, Moss, Bernard
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035496/
https://ncbi.nlm.nih.gov/pubmed/32019881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921098117
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