Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design

Cumulative evidence supports a role for neutralizing antibodies contributing to spontaneous viral clearance during acute hepatitis C virus (HCV) infection. Information on the timing and specificity of the B cell response associated with clearance is crucial to inform vaccine design. From an individu...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Keck, Zhen-Yong, Pierce, Brian G., Lau, Patrick, Lu, Janine, Wang, Yong, Underwood, Alexander, Bull, Rowena A., Prentoe, Jannick, Velázquez-Moctezuma, Rodrigo, Walker, Melanie R., Luciani, Fabio, Guest, Johnathan D., Fauvelle, Catherine, Baumert, Thomas F., Bukh, Jens, Lloyd, Andrew R., Foung, Steven K. H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542541/
https://ncbi.nlm.nih.gov/pubmed/31100098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007772
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