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mRNA association by aminoacyl tRNA synthetase occurs at a putative anticodon mimic and autoregulates translation in response to tRNA levels

Aminoacyl-tRNA synthetases (aaRSs) are well studied for their role in binding and charging tRNAs with cognate amino acids. Recent RNA interactome studies had suggested that these enzymes can also bind polyadenylated RNAs. Here, we explored the mRNA repertoire bound by several yeast aaRSs. RNA immuno...

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Bibliographic Details
Published in:PLoS Biol
Main Authors: Levi, Ofri, Arava, Yoav
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542539/
https://ncbi.nlm.nih.gov/pubmed/31100060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000274
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