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mRNA association by aminoacyl tRNA synthetase occurs at a putative anticodon mimic and autoregulates translation in response to tRNA levels

Aminoacyl-tRNA synthetases (aaRSs) are well studied for their role in binding and charging tRNAs with cognate amino acids. Recent RNA interactome studies had suggested that these enzymes can also bind polyadenylated RNAs. Here, we explored the mRNA repertoire bound by several yeast aaRSs. RNA immuno...

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Détails bibliographiques
Publié dans:PLoS Biol
Auteurs principaux: Levi, Ofri, Arava, Yoav
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542539/
https://ncbi.nlm.nih.gov/pubmed/31100060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000274
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