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mRNA association by aminoacyl tRNA synthetase occurs at a putative anticodon mimic and autoregulates translation in response to tRNA levels

Aminoacyl-tRNA synthetases (aaRSs) are well studied for their role in binding and charging tRNAs with cognate amino acids. Recent RNA interactome studies had suggested that these enzymes can also bind polyadenylated RNAs. Here, we explored the mRNA repertoire bound by several yeast aaRSs. RNA immuno...

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Publicat a:PLoS Biol
Autors principals: Levi, Ofri, Arava, Yoav
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542539/
https://ncbi.nlm.nih.gov/pubmed/31100060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000274
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