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Cell-free production of trimeric influenza hemagglutinin head domain proteins as vaccine antigens

In order to effectively combat pandemic influenza threats, there is a need for more rapid and robust vaccine production methods. In this paper, we demonstrate E. coli-based cell-free protein synthesis (CFPS) as a method to rapidly produce domains from the protein hemagglutinin (HA), which is present...

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Detalles Bibliográficos
Publicado en:Biotechnol Bioeng
Main Authors: Welsh, John P., Lu, Yuan, He, Xiao-Song, Greenberg, Harry B., Swartz, James R.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542462/
https://ncbi.nlm.nih.gov/pubmed/22729608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.24581
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