Functional characterization of hepatitis B virus core promoter mutants revealed transcriptional interference among co-terminal viral mRNAs

Hepatitis B virus (HBV) has a 3.2 kb circular DNA genome. It employs four promoters in conjunction with a single polyadenylation signal to generate 3.5, 2.4, 2.1 and 0.7 kb co-terminal RNAs. The 3.5 kb RNA is subdivided into the precore RNA for e-antigen expression and pregenomic RNA for genome repl...

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Detalhes bibliográficos
Publicado no:J Gen Virol
Main Authors: Chen, Chaoyang, Jia, Haodi, Zhang, Fei, Qin, Yanli, Zong, Li, Yuan, Quan, Wang, Yongxiang, Xia, Ningshao, Li, Jisu, Wen, Yumei, Tong, Shuping
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2016
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Standard
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6542254/
https://ncbi.nlm.nih.gov/pubmed/27558941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000590
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