Evaluation and statistical optimization of a method for methylated cell-free fetal DNA extraction from maternal plasma

PURPOSE: Methylated cell-free fetal DNA (cffDNA) in maternal plasma can potentially be used as a biomarker for accurate noninvasive prenatal testing (NIPT) of fetal disorders. Recovery and purification of cffDNA are key steps for downstream applications. In this study, we aimed to developed and eval...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Assist Reprod Genet
Main Authors: Akbariqomi, Mostafa, Heidari, Reza, Gargari, Soraya Saleh, Omrani, Mir Davood, Rigi, Garshasb, Sanikhani, Nafiseh Sadat, Kooshki, Hamid, Mahmoudian, Fatemeh, Mazlomi, Mohammad Ali, Tavoosidana, Gholamreza
פורמט: Artigo
שפה:Inglês
יצא לאור: Springer US 2019
נושאים:
Technological Innovations
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541686/
https://ncbi.nlm.nih.gov/pubmed/30820784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-019-01425-w
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