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Evaluation and statistical optimization of a method for methylated cell-free fetal DNA extraction from maternal plasma
PURPOSE: Methylated cell-free fetal DNA (cffDNA) in maternal plasma can potentially be used as a biomarker for accurate noninvasive prenatal testing (NIPT) of fetal disorders. Recovery and purification of cffDNA are key steps for downstream applications. In this study, we aimed to developed and eval...
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| Pubblicato in: | J Assist Reprod Genet |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer US
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541686/ https://ncbi.nlm.nih.gov/pubmed/30820784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-019-01425-w |
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