Evaluation and statistical optimization of a method for methylated cell-free fetal DNA extraction from maternal plasma

PURPOSE: Methylated cell-free fetal DNA (cffDNA) in maternal plasma can potentially be used as a biomarker for accurate noninvasive prenatal testing (NIPT) of fetal disorders. Recovery and purification of cffDNA are key steps for downstream applications. In this study, we aimed to developed and eval...

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Udgivet i:J Assist Reprod Genet
Main Authors: Akbariqomi, Mostafa, Heidari, Reza, Gargari, Soraya Saleh, Omrani, Mir Davood, Rigi, Garshasb, Sanikhani, Nafiseh Sadat, Kooshki, Hamid, Mahmoudian, Fatemeh, Mazlomi, Mohammad Ali, Tavoosidana, Gholamreza
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2019
Fag:
Technological Innovations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541686/
https://ncbi.nlm.nih.gov/pubmed/30820784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-019-01425-w
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