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Early divergence of mutational processes in human fetal tissues
A developing human fetus needs to balance rapid cellular expansion with maintaining genomic stability. Here, we accurately quantified and characterized somatic mutation accumulation in fetal tissues by analyzing individual stem cells from human fetal liver and intestine. Fetal mutation rates were ab...
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| Vydáno v: | Sci Adv |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Association for the Advancement of Science
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541467/ https://ncbi.nlm.nih.gov/pubmed/31149636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw1271 |
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