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Obstacles to scanning by RNase E govern bacterial mRNA lifetimes by hindering access to distal cleavage sites
The diversity of mRNA lifetimes in bacterial cells is difficult to reconcile with the relaxed cleavage-site specificity of RNase E, the endonuclease most important for governing mRNA degradation. This enzyme has generally been thought to locate cleavage sites by searching freely in three dimensions....
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| Veröffentlicht in: | Mol Cell |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541411/ https://ncbi.nlm.nih.gov/pubmed/30852060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.01.044 |
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