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Simple Alkanoyl Acylating Agents for Reversible RNA Functionalization and Control
We describe the synthesis and RNA acylation activity of a series of minimalist azidoalkanoyl imidazole reagents, with the aim of functionalizing RNA at 2’-hydroxyl groups at stoichiometric to superstoichiometric levels. We find marked effects of small structural changes on their ability to acylate a...
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| Udgivet i: | Chem Commun (Camb) |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541391/ https://ncbi.nlm.nih.gov/pubmed/30977472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc01598a |
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