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Fibrous Dysplasia of Bone and McCune-Albright Syndrome: a Bench to Bedside Review
Fibrous dysplasia is an uncommon mosaic disorder in which bone is replaced by structurally unsound fibro-osseous tissue. It is caused by the sporadic post-zygotic activating mutations in GNAS, resulting in dysregulated Gα(S)-protein signaling in affected tissues. This manifests on a broad clinical s...
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| Publicado no: | Calcif Tissue Int |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6541017/ https://ncbi.nlm.nih.gov/pubmed/31037426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-019-00550-z |
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