Effects of CC chemokine receptor 5 (CCR5) inhibitors on the dynamics of CCR5 and CC-chemokine-CCR5 interactions

BACKGROUND: This study aimed to examine how CC chemokine receptor 5 (CCR5) inhibitors (aplaviroc [APL], TAK779 and maraviroc [MVC]) interact with CCR5 and affect its dynamics and physiological CC-chemokine–CCR5 interactions. METHODS: A yellow fluorescent protein (YFP)-tagged CCR5-expressing U373-MAG...

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Publicat a:Antivir Ther
Autors principals: Nakata, Hirotomo, Kruhlak, Michael, Kamata, Wakako, Ogata-Aoki, Hiromi, Li, Jianfeng, Maeda, Kenji, Ghosh, Arun K, Mitsuya, Hiroaki
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540997/
https://ncbi.nlm.nih.gov/pubmed/20516552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP1529
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