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The Selective Rat Toxicant Norbormide Blocks K(ATP) Channels in Smooth Muscle Cells But Not in Insulin-Secreting Cells

Norbormide is a toxicant selective for rats to which it induces a widespread vasoconstriction. In a recent paper, we hypothesized a role of ATP-sensitive potassium (K(ATP)) channels in norbormide-induced vasoconstriction. The current study was undertaken to verify this hypothesis by comparing the ef...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Saponara, Simona, Fusi, Fabio, Spiga, Ottavia, Trezza, Alfonso, Hopkins, Brian, Brimble, Margaret A., Rennison, David, Bova, Sergio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540933/
https://ncbi.nlm.nih.gov/pubmed/31191321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00598
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