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Integrated gut and liver microphysiological systems for quantitative in vitro pharmacokinetic studies

Investigation of the pharmacokinetics (PK) of a compound is of significant importance during the early stages of drug development and therefore several in vitro systems are routinely employed for this purpose. However, the need for more physiologically realistic in vitro models has recently fueled t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:AAPS J
Päätekijät: Tsamandouras, Nikolaos, Chen, Wen Li Kelly, Edington, Collin D., Stokes, Cynthia L., Griffith, Linda G., Cirit, Murat
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540747/
https://ncbi.nlm.nih.gov/pubmed/28752430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-017-0122-4
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