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Absence of the β1 subunit of AMP‐activated protein kinase reduces myofibroblast infiltration of the kidneys in early diabetes

Activation of the heterotrimeric energy‐sensing kinase AMP‐activated protein kinase (AMPK) has been reported to improve experimental diabetic kidney disease. We examined the effect of type 1 diabetes in wild‐type (WT) mice and mice lacking the β1 subunit of AMPK (AMPK β1(−/−) mice), which have reduc...

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Detalhes bibliográficos
Publicado no:Int J Exp Pathol
Main Authors: Choy, Suet‐Wan, Fraser, Scott A., Katerelos, Marina, Galic, Sandra, Kemp, Bruce E., Mount, Peter F., Power, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540654/
https://ncbi.nlm.nih.gov/pubmed/31025787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/iep.12313
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