Regulation of the renal-specific Na(+)–K(+)–2Cl(−) co-transporter NKCC2 by AMP-activated protein kinase (AMPK)

The renal-specific NKCC2 (Na(+)–K(+)–2Cl(−) co-transporter 2) is regulated by changes in phosphorylation state, however, the phosphorylation sites and kinases responsible have not been fully elucidated. In the present study, we demonstrate that the metabolic sensing kinase AMPK (AMP-activated protei...

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Bibliographic Details
Main Authors: Fraser, Scott A., Gimenez, Ignacio, Cook, Natasha, Jennings, Ian, Katerelos, Marina, Katsis, Frosa, Levidiotis, Vicki, Kemp, Bruce E., Power, David A.
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2007
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1925243/
https://ncbi.nlm.nih.gov/pubmed/17341212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061850
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