Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B

Background: KDM5 enzymes are H3K4 specific histone demethylases involved in transcriptional regulation and DNA repair. These proteins are overexpressed in different kinds of cancer, including breast, prostate and bladder carcinomas, with positive effects on cancer proliferation and chemoresistance....

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Molecules
Autori principali: Pippa, Simone, Mannironi, Cecilia, Licursi, Valerio, Bombardi, Luca, Colotti, Gianni, Cundari, Enrico, Mollica, Adriano, Coluccia, Antonio, Naccarato, Valentina, La Regina, Giuseppe, Silvestri, Romano, Negri, Rodolfo
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540222/
https://ncbi.nlm.nih.gov/pubmed/31060229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24091739
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi