3-Methylcholanthrene Induces Chylous Ascites in TCDD-Inducible Poly-ADP-Ribose Polymerase (Tiparp) Knockout Mice

TCDD-inducible poly-ADP-ribose polymerase (TIPARP) is an aryl hydrocarbon receptor (AHR) target gene that functions as part of a negative feedback loop to repress AHR activity. Tiparp(−/−) mice exhibit increased sensitivity to the toxicological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD),...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Cho, Tiffany E., Bott, Debbie, Ahmed, Shaimaa, Hutin, David, Gomez, Alvin, Tamblyn, Laura, Zhou, Angela C., Watts, Tania H., Grant, Denis M., Matthews, Jason
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6540065/
https://ncbi.nlm.nih.gov/pubmed/31083300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092312
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