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Computational Aminoacyl-tRNA Synthetase Library Design for Photocaged Tyrosine
Engineering aminoacyl-tRNA synthetases (aaRSs) provides access to the ribosomal incorporation of noncanonical amino acids via genetic code expansion. Conventional targeted mutagenesis libraries with 5–7 positions randomized cover only marginal fractions of the vast sequence space formed by up to 30...
Guardat en:
| Publicat a: | Int J Mol Sci |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6539999/ https://ncbi.nlm.nih.gov/pubmed/31083552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092343 |
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