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Structure/Activity Analysis of TASK-3 Channel Antagonists Based on a 5,6,7,8 tetrahydropyrido[4,3-d]pyrimidine

TASK-3 potassium (K(+)) channels are highly expressed in the central nervous system, regulating the membrane potential of excitable cells. TASK-3 is involved in neurotransmitter action and has been identified as an oncogenic K(+) channel. For this reason, the understanding of the action mechanism of...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ramírez, David, Bedoya, Mauricio, Kiper, Aytug K., Rinné, Susanne, Morales-Navarro, Samuel, Hernández-Rodríguez, Erix W., Sepúlveda, Francisco V., Decher, Niels, González, Wendy
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539479/
https://ncbi.nlm.nih.gov/pubmed/31067753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20092252
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