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An Oncolytic Adenovirus Vector Expressing p14 FAST Protein Induces Widespread Syncytium Formation and Reduces Tumor Growth Rate In Vivo

Intratumoral injection of oncolytic viruses provides a direct means of tumor cell destruction for inoperable tumors. Unfortunately, oncolytic vectors based on human adenovirus (HAdV) typically do not spread efficiently throughout the tumor mass, reducing the efficacy of treatment. In this study, we...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Del Papa, Josh, Petryk, Julia, Bell, John C., Parks, Robin J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6539411/
https://ncbi.nlm.nih.gov/pubmed/31193718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2019.05.001
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