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The MitoNEET Ligand NL-1 Mediates Antileukemic Activity in Drug-Resistant B-Cell Acute Lymphoblastic Leukemia

Disease relapse in B-cell acute lymphoblastic leukemia (ALL), either due to development of acquired resistance after therapy or because of de novo resistance, remains a therapeutic challenge. In the present study, we have developed a cytarabine (Ara-C)-resistant REH cell line (REH/Ara-C) as a chemor...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Geldenhuys, Werner J., Nair, Rajesh R., Piktel, Debbie, Martin, Karen H., Gibson, Laura F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538890/
https://ncbi.nlm.nih.gov/pubmed/31010844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.255984
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