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Novel ligands that target the mitochondrial membrane protein mitoNEET

Ligands of the thiazolidinedione (TZD) class of compounds, pioglitazone (Actos™) and rosiglitazone (Avandia™) are currently approved for treatment of type 2 diabetes and are known to bind to the PPAR-γ nuclear receptor subtype. Recent evidence suggesting PPAR-γ independent action of the TZDs led to...

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Hlavní autoři: Bieganski, Robert M., Yarmush, Martin L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477874/
https://ncbi.nlm.nih.gov/pubmed/21531159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2011.04.001
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