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The zinc transporter Slc39a5 controls glucose sensing and insulin secretion in pancreatic β-cells via Sirt1- and Pgc-1α-mediated regulation of Glut2

Zinc levels are high in pancreatic β-cells, and zinc is involved in the synthesis, processing and secretion of insulin in these cells. However, precisely how cellular zinc homeostasis is regulated in pancreatic β-cells is poorly understood. By screening the expression of 14 Slc39a metal importer fam...

詳細記述

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書誌詳細
出版年:Protein Cell
主要な著者: Wang, Xinhui, Gao, Hong, Wu, Wenhui, Xie, Enjun, Yu, Yingying, He, Xuyan, Li, Jin, Zheng, Wanru, Wang, Xudong, Cao, Xizhi, Meng, Zhuoxian, Chen, Ligong, Min, Junxia, Wang, Fudi
フォーマット: Artigo
言語:Inglês
出版事項: Higher Education Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538592/
https://ncbi.nlm.nih.gov/pubmed/30324491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-018-0580-1
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