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Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids

Herein we disclose an efficient method for the conversion of carboxylic acids to trifluoromethyl groups via the combination of photoredox and copper catalysis. This transformation tolerates a wide range of functionality including heterocycles, olefins, alcohols, and strained ring systems. To demonst...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Kautzky, Jacob A., Wang, Tao, Evans, Ryan W., MacMillan, David W. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538506/
https://ncbi.nlm.nih.gov/pubmed/29754491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b02650
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