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Targeting PI3Kδ Function For Amelioration of Murine Chronic Graft-Versus-Host Disease
Chronic graft-versus-host disease is a leading cause of morbidity and mortality following allotransplant. Activated donor effector T-cells can differentiate into pathogenic T helper (Th)-17 cells and germinal center-promoting Tfollicular helper cells, resulting in cGVHD. Phosphoinositide-3-kinase-δ,...
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| 出版年: | Am J Transplant |
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6538456/ https://ncbi.nlm.nih.gov/pubmed/30748099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15305 |
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