Targeting PI3Kδ Function For Amelioration of Murine Chronic Graft-Versus-Host Disease

Chronic graft-versus-host disease is a leading cause of morbidity and mortality following allotransplant. Activated donor effector T-cells can differentiate into pathogenic T helper (Th)-17 cells and germinal center-promoting Tfollicular helper cells, resulting in cGVHD. Phosphoinositide-3-kinase-δ,...

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Detaylı Bibliyografya
Yayımlandı:Am J Transplant
Asıl Yazarlar: Paz, Katelyn, Flynn, Ryan, Du, Jing, Tannheimer, Stacey, Johnson, Amy J., Dong, Shuai, Stark, Anne-Katrien, Okkenhaug, Klaus, Panoskaltsis-Mortari, Angela, Sage, Peter T., Sharpe, Arlene H., Luznik, Leo, Ritz, Jerome, Soiffer, Robert J., Cutler, Corey S., Koreth, John, Antin, Joseph H., Miklos, David B., MacDonald, Kelli P., Hill, Geoffrey R., Maillard, Ivan, Serody, Jonathan S., Murphy, William J., Munn, David H., Feser, Colby, Zaiken, Michael, Vanhaesebroeck, Bart, Turka, Laurence A., Byrd, John C., Blazar, Bruce R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538456/
https://ncbi.nlm.nih.gov/pubmed/30748099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15305
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