Targeting PI3Kδ Function For Amelioration of Murine Chronic Graft-Versus-Host Disease

Chronic graft-versus-host disease is a leading cause of morbidity and mortality following allotransplant. Activated donor effector T-cells can differentiate into pathogenic T helper (Th)-17 cells and germinal center-promoting Tfollicular helper cells, resulting in cGVHD. Phosphoinositide-3-kinase-δ,...

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書誌詳細
出版年:Am J Transplant
主要な著者: Paz, Katelyn, Flynn, Ryan, Du, Jing, Tannheimer, Stacey, Johnson, Amy J., Dong, Shuai, Stark, Anne-Katrien, Okkenhaug, Klaus, Panoskaltsis-Mortari, Angela, Sage, Peter T., Sharpe, Arlene H., Luznik, Leo, Ritz, Jerome, Soiffer, Robert J., Cutler, Corey S., Koreth, John, Antin, Joseph H., Miklos, David B., MacDonald, Kelli P., Hill, Geoffrey R., Maillard, Ivan, Serody, Jonathan S., Murphy, William J., Munn, David H., Feser, Colby, Zaiken, Michael, Vanhaesebroeck, Bart, Turka, Laurence A., Byrd, John C., Blazar, Bruce R.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538456/
https://ncbi.nlm.nih.gov/pubmed/30748099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15305
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