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Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease

Novel therapies for chronic graft-versus-host disease (cGVHD) are needed. Aberrant B-cell activation has been demonstrated in mice and humans with cGVHD. Having previously found that human cGVHD B cells are activated and primed for survival, we sought to further evaluate the role of the spleen tyros...

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Bibliografische gegevens
Gepubliceerd in:Blood
Hoofdauteurs: Flynn, Ryan, Allen, Jessica L., Luznik, Leo, MacDonald, Kelli P., Paz, Katelyn, Alexander, Kylie A., Vulic, Ante, Du, Jing, Panoskaltsis-Mortari, Angela, Taylor, Patricia A., Poe, Jonathan C., Serody, Jonathan S., Murphy, William J., Hill, Geoffrey R., Maillard, Ivan, Koreth, John, Cutler, Corey S., Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome, Chao, Nelson J., Clynes, Raphael A., Sarantopoulos, Stefanie, Blazar, Bruce R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481596/
https://ncbi.nlm.nih.gov/pubmed/25852057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-595470
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