Targeting Syk-activated B cells in murine and human chronic graft-versus-host disease

Novel therapies for chronic graft-versus-host disease (cGVHD) are needed. Aberrant B-cell activation has been demonstrated in mice and humans with cGVHD. Having previously found that human cGVHD B cells are activated and primed for survival, we sought to further evaluate the role of the spleen tyros...

Full description

Saved in:
Bibliographic Details
Published in:Blood
Main Authors: Flynn, Ryan, Allen, Jessica L., Luznik, Leo, MacDonald, Kelli P., Paz, Katelyn, Alexander, Kylie A., Vulic, Ante, Du, Jing, Panoskaltsis-Mortari, Angela, Taylor, Patricia A., Poe, Jonathan C., Serody, Jonathan S., Murphy, William J., Hill, Geoffrey R., Maillard, Ivan, Koreth, John, Cutler, Corey S., Soiffer, Robert J., Antin, Joseph H., Ritz, Jerome, Chao, Nelson J., Clynes, Raphael A., Sarantopoulos, Stefanie, Blazar, Bruce R.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2015
Subjects:
Transplantation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4481596/
https://ncbi.nlm.nih.gov/pubmed/25852057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-595470
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items