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Regulation of the Unfolded Protein Response in Yeast by Oxidative Stress
In the unfolded protein response (UPR), Ire1 activates Hac1 to coordinate the transcription of hundreds of genes to mitigate ER stress. Recent work in C. elegans suggests that oxidative stress inhibits this canonical Ire1 signaling pathway, activating instead an anti-oxidant stress response. We soug...
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| Publicado no: | FEBS Lett |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6538422/ https://ncbi.nlm.nih.gov/pubmed/31002390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13389 |
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