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Regulation of the Unfolded Protein Response in Yeast by Oxidative Stress

In the unfolded protein response (UPR), Ire1 activates Hac1 to coordinate the transcription of hundreds of genes to mitigate ER stress. Recent work in C. elegans suggests that oxidative stress inhibits this canonical Ire1 signaling pathway, activating instead an anti-oxidant stress response. We soug...

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Detalles Bibliográficos
Publicado en:FEBS Lett
Main Authors: Guerra-Moreno, Angel, Ang, Jessie, Welsch, Hendrik, Jochem, Marco, Hanna, John
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538422/
https://ncbi.nlm.nih.gov/pubmed/31002390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13389
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