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Tmc1 Is a Dynamically Regulated Effector of the Rpn4 Proteotoxic Stress Response

The ubiquitin-proteasome system represents the major pathway of selective intracellular protein degradation in eukaryotes. Misfolded proteins represent an important class of substrates for this pathway, and the failure to destroy misfolded proteins is associated with a number of human diseases. The...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Guerra-Moreno, Angel, Hanna, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938195/
https://ncbi.nlm.nih.gov/pubmed/27226598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.726398
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