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Protein Degradation and the Pathologic Basis of Disease

The abundance of any protein is determined by the balance of protein synthesis and protein degradation. Regulated protein degradation has emerged as a powerful means of precisely controlling individual protein abundance within cells and is largely mediated by the ubiquitin-proteasome system (UPS). B...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Hanna, John, Guerra-Moreno, Angel, Ang, Jessie, Micoogullari, Yagmur
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315326/
https://ncbi.nlm.nih.gov/pubmed/30312581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.09.004
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