Autophagy links antimicrobial activity with antigen presentation in Langerhans cells

DC, through the uptake, processing, and presentation of antigen, are responsible for activation of T cell responses to defend the host against infection, yet it is not known if they can directly kill invading bacteria. Here, we studied in human leprosy, how Langerhans cells (LC), specialized DC, con...

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Publicado en:JCI Insight
Autores principales: Dang, Angeline Tilly, Teles, Rosane M.B., Liu, Phillip T., Choi, Aaron, Legaspi, Annalisa, Sarno, Euzenir N., Ochoa, Maria T., Parvatiyar, Kislay, Cheng, Genhong, Gilliet, Michel, Bloom, Barry R., Modlin, Robert L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538337/
https://ncbi.nlm.nih.gov/pubmed/30996142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126955
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