Interleukin-4 Regulates the Expression of CD209 and Subsequent Uptake of Mycobacterium leprae by Schwann Cells in Human Leprosy

The ability of microbial pathogens to target specific cell types is a key aspect of the pathogenesis of infectious disease. Mycobacterium leprae, by infecting Schwann cells, contributes to nerve injury in patients with leprosy. Here, we investigated mechanisms of host-pathogen interaction in the per...

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Bibliografiske detaljer
Main Authors: Teles, Rosane M. B., Krutzik, Stephan R., Ochoa, Maria T., Oliveira, Rosane B., Sarno, Euzenir N., Modlin, Robert L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976321/
https://ncbi.nlm.nih.gov/pubmed/20713631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00454-10
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