Expression of Toll-Like Receptor 2 on Human Schwann Cells: a Mechanism of Nerve Damage in Leprosy

Nerve damage is a clinical hallmark of leprosy and a major source of patient morbidity. We investigated the possibility that human Schwann cells are susceptible to cell death through the activation of Toll-like receptor 2 (TLR2), a pattern recognition receptor of the innate immune system. TLR2 was d...

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Bibliografiske detaljer
Main Authors: Oliveira, Rosane B., Ochoa, Maria T., Sieling, Peter A., Rea, Thomas H., Rambukkana, Anura, Sarno, Euzenir N., Modlin, Robert L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC148832/
https://ncbi.nlm.nih.gov/pubmed/12595460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.3.1427-1433.2003
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