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Autophagy links antimicrobial activity with antigen presentation in Langerhans cells

DC, through the uptake, processing, and presentation of antigen, are responsible for activation of T cell responses to defend the host against infection, yet it is not known if they can directly kill invading bacteria. Here, we studied in human leprosy, how Langerhans cells (LC), specialized DC, con...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Dang, Angeline Tilly, Teles, Rosane M.B., Liu, Phillip T., Choi, Aaron, Legaspi, Annalisa, Sarno, Euzenir N., Ochoa, Maria T., Parvatiyar, Kislay, Cheng, Genhong, Gilliet, Michel, Bloom, Barry R., Modlin, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538337/
https://ncbi.nlm.nih.gov/pubmed/30996142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126955
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