Autophagy links antimicrobial activity with antigen presentation in Langerhans cells

DC, through the uptake, processing, and presentation of antigen, are responsible for activation of T cell responses to defend the host against infection, yet it is not known if they can directly kill invading bacteria. Here, we studied in human leprosy, how Langerhans cells (LC), specialized DC, con...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Dang, Angeline Tilly, Teles, Rosane M.B., Liu, Phillip T., Choi, Aaron, Legaspi, Annalisa, Sarno, Euzenir N., Ochoa, Maria T., Parvatiyar, Kislay, Cheng, Genhong, Gilliet, Michel, Bloom, Barry R., Modlin, Robert L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2019
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538337/
https://ncbi.nlm.nih.gov/pubmed/30996142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.126955
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