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B lymphocytes protect islet β cells in diabetes-prone NOD mice treated with imatinib
Imatinib (Gleevec) reverses type 1 diabetes (T1D) in NOD mice and is currently in clinical trials in individuals with recent-onset disease. While research has demonstrated that imatinib protects islet β cells from the harmful effects of ER stress, the role the immune system plays in its reversal of...
Sparad:
| I publikationen: | JCI Insight |
|---|---|
| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Clinical Investigation
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6538336/ https://ncbi.nlm.nih.gov/pubmed/30964447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125317 |
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