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Impact of Pdx1-associated chromatin modifiers on islet β-cells
Diabetes mellitus arises from insufficient insulin secretion from pancreatic islet β-cells. In type 2 diabetes (T2D), β-cell dysfunction is associated with inactivation and/or loss of transcription factor activity, including Pdx1. Notably, this particular transcription factor is viewed as a master r...
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| Publicado no: | Diabetes Obes Metab |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5918695/ https://ncbi.nlm.nih.gov/pubmed/27615141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/dom.12730 |
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