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Dynamic recruitment of functionally distinct Swi/Snf chromatin remodeling complexes modulates Pdx1 activity in islet beta cells

Pdx1 is a transcription factor of fundamental importance to pancreas formation and adult islet β-cell function. However, little is known about the positive- and negative-acting coregulators recruited to mediate transcriptional control. Here we isolated numerous Pdx1-interacting factors possessing a...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: McKenna, Brian, Guo, Min, Reynolds, Albert, Hara, Manami, Stein, Roland
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651178/
https://ncbi.nlm.nih.gov/pubmed/25801033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.02.054
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