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Sclerostin inhibition alleviates breast cancer–induced bone metastases and muscle weakness
Breast cancer bone metastases often cause a debilitating incurable condition with osteolytic lesions, muscle weakness, and a high mortality. Current treatment comprises chemotherapy, irradiation, surgery, and antiresorptive drugs that restrict but do not revert bone destruction. In hormone receptor–...
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| Pubblicato in: | JCI Insight |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6538320/ https://ncbi.nlm.nih.gov/pubmed/30965315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125543 |
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