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Resolving Adeno-Associated Viral Particle Diversity With Charge Detection Mass Spectrometry
Recombinant adeno-associated viruses (AAVs) are promising vectors for human gene therapy. However, current methods for evaluating AAV particle populations and vector purity are inefficient and low resolution. Here, we show that charge detection mass spectrometry (CDMS) can resolve capsids that conta...
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| Udgivet i: | Anal Chem |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6537880/ https://ncbi.nlm.nih.gov/pubmed/27310298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b00883 |
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