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Resolving Adeno-Associated Viral Particle Diversity With Charge Detection Mass Spectrometry
Recombinant adeno-associated viruses (AAVs) are promising vectors for human gene therapy. However, current methods for evaluating AAV particle populations and vector purity are inefficient and low resolution. Here, we show that charge detection mass spectrometry (CDMS) can resolve capsids that conta...
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| Publié dans: | Anal Chem |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6537880/ https://ncbi.nlm.nih.gov/pubmed/27310298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.6b00883 |
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