Association of Patisiran, an RNA Interference Therapeutic, With Regional Left Ventricular Myocardial Strain in Hereditary Transthyretin Amyloidosis: The APOLLO Study

IMPORTANCE: Patients with cardiac amyloidosis demonstrate reduced myocardial strain with associated sparing of the cardiac apex. In the APOLLO randomized clinical trial, patisiran, an RNA interference therapeutic that inhibits transthyretin synthesis, improved left ventricular (LV) global longitudin...

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Xehetasun bibliografikoak
Argitaratua izan da:JAMA Cardiol
Egile Nagusiak: Minamisawa, Masatoshi, Claggett, Brian, Adams, David, Kristen, Arnt V., Merlini, Giampaolo, Slama, Michel S., Dispenzieri, Angela, Shah, Amil M., Falk, Rodney H., Karsten, Verena, Sweetser, Marianne T., Chen, Jihong, Riese, Richard, Vest, John, Solomon, Scott D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Medical Association 2019
Gaiak:
Brief Report
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537803/
https://ncbi.nlm.nih.gov/pubmed/30878017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamacardio.2019.0849
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