TFEB Probably Involved in Midazolam-Disturbed Lysosomal Homeostasis and Its Induced β-Amyloid Accumulation

Alzheimer’s disease (AD) is one of the most common neurodegenerative diseases, and β-amyloid (Aβ) plays a leading role in the pathogenesis of AD. The transcription factor EB (TFEB), a main regulating factor of autophagy and lysosome biosynthesis, is involved in the pathogenesis of AD by regulating a...

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Detalhes bibliográficos
Publicado no:Front Hum Neurosci
Main Authors: Cheng, Dan, Tan, Qilian, Zhu, Qianyun, Zhang, Jiqian, Han, Xiaoyu, Fang, Panpan, Jin, Weilin, Liu, Xuesheng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6536689/
https://ncbi.nlm.nih.gov/pubmed/31164812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnhum.2019.00108
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