Pro-Apoptotic Effects of Estetrol on Long-Term Estrogen-Deprived Breast Cancer Cells and at Low Doses on Hormone-Sensitive Cells

PURPOSE: Postmenopausal women with estrogen receptor-positive breast cancers often respond initially to tamoxifen or aromatase inhibitor therapy. Resistance to these treatments usually develops within 12 to 18 months. Clinical studies have demonstrated that high-dose estrogen can induce regression o...

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Detalles Bibliográficos
Publicado en:Breast Cancer (Auckl)
Autores principales: Yue, Wei, Verhoeven, Carole, Bernnink, Herjan Coelingh, Wang, Ji-ping, Santen, Richard J
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2019
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535901/
https://ncbi.nlm.nih.gov/pubmed/31205415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1178223419844198
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