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Broad-Spectrum Proteome Editing with an Engineered Bacterial Ubiquitin Ligase Mimic
[Image: see text] Manipulation of the ubiquitin-proteasome pathway to achieve targeted silencing of cellular proteins has emerged as a reliable and customizable strategy for remodeling the mammalian proteome. One such approach involves engineering bifunctional proteins called ubiquibodies that are c...
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| Publicado en: | ACS Cent Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical Society
2019
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6535771/ https://ncbi.nlm.nih.gov/pubmed/31139721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.9b00127 |
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