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Efficacy of Olorofim (F901318) against Aspergillus fumigatus, A. nidulans, and A. tanneri in Murine Models of Profound Neutropenia and Chronic Granulomatous Disease

The emergence of azole resistance in Aspergillus fumigatus as well as an increasing frequency of multiresistant cryptic Aspergillus spp. necessitates exploration of new classes of antifungals. Olorofim (formerly F901318) is a new fungicidal agent that prevents the growth of ascomycetous mold species...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Seyedmousavi, S., Chang, Y. C., Law, D., Birch, M., Rex, J. H., Kwon-Chung, K. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6535528/
https://ncbi.nlm.nih.gov/pubmed/30885903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00129-19
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